(Multiple Sclerosis (MS) )
Multiple Sclerosis is a chronic-disease of the central nervous system, or CNS, which is comprised of the brain and spinal cord. The CNS sends and receives signals through a network of nerves insulated by a protective protein coating called myelin. In MS, myelin is broken down, causing a disruption in these signals.
Multiple Sclerosis is a chronic disease of the central nervous system, or CNS, which is comprised of the brain and spinal cord. The CNS sends and receives signals through a network of nerves insulated by a protective protein coating called myelin. In MS, myelin is broken down, causing a disruption in these signals.Demyelination is a hallmark of this disease; a process researchers believe may begin before symptoms appear. This furthers the case for early intervention up on diagnosis of relapsing-remitting multiple sclerosis. Mild symptoms often include vision or dexterity problems, numbness or tingling sensations. In some patients, more severe symptoms may eventually include a partial or complete loss of vision or mobility.
MULTIPLE SCLEROSIS IS CHARACTERIZED BY
Attacks –“Flare-ups” or exacerbations –which may be associated with plaques that prevent conduction of nerve impulses in the CNS. A period of exacerbation is also known as a relapse.
In relapsing-remitting multiple sclerosis, the presumed path of MS is as follows:
1. Normally functioning nerves are insulated by a protective protein coating called myelin.
2. In multiple sclerosis, myelin is broken down, causing disruptions in the signals sent to and from the brain.
3. Natural immune cells, or T cells, are believed to bind with lost myelin proteins and become pro inflammatory.
4. These harmful T cells are thought to cross the protective blood-brain barrier into the central nervous system (CNS).
5. Inside the CNS, the T cells bind with myelin proteins and release-inflammatory substances (cytokines) believed to contribute to myelin breakdown.
HOW MS AFFECTS PEOPLE?
While many people living with MS are affected with some level of disability, this is not true of everyone ... and among those who do have a level of disability,this level varies greatly. Studies have shown that a majority of persons living with MS lead fairly normal lives. MS symptoms may fluctuate, and they may progress in severity. And many people have periods of no apparent symptoms that may last many years, but lesions can still be forming in the CNS undetected.
Be cause MS can vary so widely from one person to another, no predictions of the outcome for any individual can be made. Statistically, however, a person with MS today has good reason for optimism – especially with early treatment to minimize the number of attacks.
WHO GETS MS?
Multiple sclerosis is generally diagnosed in individuals between the ages of 20 and40.Women develop MS at a rate of two to three times that of men . MS occurs most frequently in “temperate zones” of neither extreme heat nor cold.
In the United States, it is estimated that approximately 350,000 people are living with multiple sclerosis, and nearly 200 cases are diagnosed every week.
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